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Class: GeneToEntityAssociationMixin

classDiagram class GeneToEntityAssociationMixin GeneToEntityAssociationMixin <|-- GeneToPathwayAssociation GeneToEntityAssociationMixin <|-- GeneToPhenotypicFeatureAssociation GeneToEntityAssociationMixin <|-- GeneToDiseaseAssociation GeneToEntityAssociationMixin <|-- CausalGeneToDiseaseAssociation GeneToEntityAssociationMixin <|-- CorrelatedGeneToDiseaseAssociation GeneToEntityAssociationMixin <|-- DruggableGeneToDiseaseAssociation GeneToEntityAssociationMixin : object GeneToEntityAssociationMixin --|> NamedThing : object GeneToEntityAssociationMixin : predicate GeneToEntityAssociationMixin : subject GeneToEntityAssociationMixin --|> GeneOrGeneProduct : subject

Slots

Name Cardinality and Range Inheritance Examples
subject:
gene that is the subject of the association 		1
GeneOrGeneProduct		 direct
predicate:
Has a value from the Biolink 'related_to' hierarchy. In RDF, this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats 		1
Uriorcurie		 direct
object:
connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. 		1
NamedThing		 direct

Mixin Usage

mixed into description
GeneToPathwayAssociation An interaction between a gene or gene product and a biological process or pathway.
GeneToPhenotypicFeatureAssociation An association between a gene or gene product and a phenotypic feature, where variation in the gene is correlated with the phenotypic feature.
GeneToDiseaseAssociation An association between a gene or gene product and a disease, where variation in the gene is correlated with the disease.
CausalGeneToDiseaseAssociation An association between a gene and a disease where variation in the gene has been shown to have a causal role in the disease.
CorrelatedGeneToDiseaseAssociation An association between a gene (or gene product) and a disease for which the gene is statistically correlated with the disease rather than asserted as causal. Such associations typically derive from GWAS, co-occurrence analyses, or other statistical methods, and are annotated with scores such as a z-score or a diseases confidence score.
DruggableGeneToDiseaseAssociation An association between a gene (or gene product) and a disease in which the gene is classified by its druggability (e.g., via the IDG/Pharos target development-level tiers).

LinkML Source

name: gene to entity association mixin
from_schema: https://w3id.org/biolink/vocab/
mixin: true
slots:
- subject
- predicate
- object
slot_usage:
  subject:
    name: subject
    description: gene that is the subject of the association
    range: gene or gene product
defining_slots:
- subject