Class: AnatomicalEntityHasPartAnatomicalEntityAssociation
Description: A relationship between two anatomical entities where the relationship is mereological, i.e the two entities are related by parthood, that is, the subject is has the object entity as a part (the expected predicate is "biolink:has_part" or suitable predicate slots inheriting from it, i.e., "biolink:has_plasma_membrane_part", "biolink:has_variant_part", etc.). This includes relationships between cells and cellular components, between issues and cells, whole organisms and tissues.
classDiagram
class AnatomicalEntityHasPartAnatomicalEntityAssociation
AnatomicalEntityToAnatomicalEntityAssociation <|-- AnatomicalEntityHasPartAnatomicalEntityAssociation
AnatomicalEntityHasPartAnatomicalEntityAssociation : adjusted_p_value
AnatomicalEntityHasPartAnatomicalEntityAssociation : agent_type
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> AgentTypeEnum : agent_type
AnatomicalEntityHasPartAnatomicalEntityAssociation : aggregator_knowledge_source
AnatomicalEntityHasPartAnatomicalEntityAssociation : category
AnatomicalEntityHasPartAnatomicalEntityAssociation : deprecated
AnatomicalEntityHasPartAnatomicalEntityAssociation : description
AnatomicalEntityHasPartAnatomicalEntityAssociation : elevate_to_prediction
AnatomicalEntityHasPartAnatomicalEntityAssociation : evidence_count
AnatomicalEntityHasPartAnatomicalEntityAssociation : has_attribute
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> Attribute : has_attribute
AnatomicalEntityHasPartAnatomicalEntityAssociation : has_confidence_score
AnatomicalEntityHasPartAnatomicalEntityAssociation : has_evidence
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> InformationContentEntity : has_evidence
AnatomicalEntityHasPartAnatomicalEntityAssociation : has_evidence_of_type
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> EvidenceType : has_evidence_of_type
AnatomicalEntityHasPartAnatomicalEntityAssociation : has_supporting_studies
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> Study : has_supporting_studies
AnatomicalEntityHasPartAnatomicalEntityAssociation : id
AnatomicalEntityHasPartAnatomicalEntityAssociation : iri
AnatomicalEntityHasPartAnatomicalEntityAssociation : knowledge_level
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> KnowledgeLevelEnum : knowledge_level
AnatomicalEntityHasPartAnatomicalEntityAssociation : knowledge_source
AnatomicalEntityHasPartAnatomicalEntityAssociation : name
AnatomicalEntityHasPartAnatomicalEntityAssociation : negated
AnatomicalEntityHasPartAnatomicalEntityAssociation : object
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> AnatomicalEntity : object
AnatomicalEntityHasPartAnatomicalEntityAssociation : object_category
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> OntologyClass : object_category
AnatomicalEntityHasPartAnatomicalEntityAssociation : object_category_closure
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> OntologyClass : object_category_closure
AnatomicalEntityHasPartAnatomicalEntityAssociation : object_closure
AnatomicalEntityHasPartAnatomicalEntityAssociation : object_feature_name
AnatomicalEntityHasPartAnatomicalEntityAssociation : object_label_closure
AnatomicalEntityHasPartAnatomicalEntityAssociation : object_namespace
AnatomicalEntityHasPartAnatomicalEntityAssociation : original_object
AnatomicalEntityHasPartAnatomicalEntityAssociation : original_predicate
AnatomicalEntityHasPartAnatomicalEntityAssociation : original_subject
AnatomicalEntityHasPartAnatomicalEntityAssociation : p_value
AnatomicalEntityHasPartAnatomicalEntityAssociation : predicate
AnatomicalEntityHasPartAnatomicalEntityAssociation : primary_knowledge_source
AnatomicalEntityHasPartAnatomicalEntityAssociation : publications
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> Publication : publications
AnatomicalEntityHasPartAnatomicalEntityAssociation : qualifier
AnatomicalEntityHasPartAnatomicalEntityAssociation : qualifiers
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> OntologyClass : qualifiers
AnatomicalEntityHasPartAnatomicalEntityAssociation : retrieval_source_ids
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> RetrievalSource : retrieval_source_ids
AnatomicalEntityHasPartAnatomicalEntityAssociation : semmed_agreement_count
AnatomicalEntityHasPartAnatomicalEntityAssociation : sources
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> RetrievalSource : sources
AnatomicalEntityHasPartAnatomicalEntityAssociation : subject
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> AnatomicalEntity : subject
AnatomicalEntityHasPartAnatomicalEntityAssociation : subject_category
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> OntologyClass : subject_category
AnatomicalEntityHasPartAnatomicalEntityAssociation : subject_category_closure
AnatomicalEntityHasPartAnatomicalEntityAssociation --|> OntologyClass : subject_category_closure
AnatomicalEntityHasPartAnatomicalEntityAssociation : subject_closure
AnatomicalEntityHasPartAnatomicalEntityAssociation : subject_feature_name
AnatomicalEntityHasPartAnatomicalEntityAssociation : subject_label_closure
AnatomicalEntityHasPartAnatomicalEntityAssociation : subject_namespace
AnatomicalEntityHasPartAnatomicalEntityAssociation : supporting_text
AnatomicalEntityHasPartAnatomicalEntityAssociation : timepoint
AnatomicalEntityHasPartAnatomicalEntityAssociation : type
AnatomicalEntityHasPartAnatomicalEntityAssociation : update_date
Inheritance
- Entity
- Association
- AnatomicalEntityToAnatomicalEntityAssociation
- AnatomicalEntityHasPartAnatomicalEntityAssociation
- AnatomicalEntityToAnatomicalEntityAssociation
- Association
Slots
| Name | Cardinality and Range | Inheritance | Examples |
|---|---|---|---|
| subject: the whole |
1 AnatomicalEntity |
Association | |
| predicate: Has a value from the Biolink 'related_to' hierarchy. In RDF, this corresponds to rdf:predicate and in Neo4j this corresponds to the relationship type. The convention is for an edge label in snake_case form. For example, biolink:related_to, biolink:causes, biolink:treats |
1 Uriorcurie |
Association | |
| object: the part |
1 AnatomicalEntity |
Association | |
| negated: if set to true, then the association is negated i.e. is not true |
0..1 Boolean |
Association | |
| qualifier: grouping slot for all qualifiers on an edge. useful for testing compliance with association classes |
0..1 String |
Association | |
| qualifiers: connects an association to qualifiers that modify or qualify the meaning of that association |
* OntologyClass |
Association | |
| publications: One or more publications that report the statement expressed in an Association, or provide information used as evidence supporting this statement. |
* Publication |
Association | |
| sources: A set of RetrievalSources, which traces where the statement expressed in an Association came from. For example, the provenance of a Gene-Chemical Edge might be traced through the Translator Resource that provided it (e.g. MolePro) to one or more intermediate aggregator resources (e.g. ChEMBL), and finally to the resource that originally created/curated it (e.g. ClinicalTrials.org). |
* RetrievalSource |
Association | |
| has_evidence_of_type: Connects an association to an evidence type ontology term. Generally represents terms from the ECO ontology. |
* EvidenceType |
Association | |
| has_evidence: Connects an association to detailed information providing supporting evidence. |
* InformationContentEntity |
Association | |
| knowledge_source: An Information Resource from which the knowledge expressed in an Association was retrieved, directly or indirectly. This can be any resource through which the knowledge passed on its way to its currently serialized form. In practice, implementers should use one of the more specific subtypes of this generic property. |
0..1 String |
Association | |
| primary_knowledge_source: The most upstream source of the knowledge expressed in an Association that an implementer can identify. Performing a rigorous analysis of upstream data providers is expected; every effort is made to catalog the most upstream source of data in this property. Only one data source should be declared primary in any association. "aggregator knowledge source" can be used to capture non-primary sources. |
0..1 String |
Association | |
| aggregator_knowledge_source: An intermediate aggregator resource from which knowledge expressed in an Association was retrieved downstream of the original source, on its path to its current serialized form. |
* String |
Association | |
| knowledge_level: Describes the level of knowledge expressed in a statement, based on the reasoning or analysis methods used to generate the statement, or the scope or specificity of what the statement expresses to be true. |
1 KnowledgeLevelEnum |
Association | knowledge_assertion, prediction, statistical_association |
| agent_type: Describes the high-level category of agent who originally generated a statement of knowledge or other type of information. |
1 AgentTypeEnum |
Association | manual_agent, automated_agent, computational_model, text_mining_agent |
| timepoint: a point in time |
0..1 TimeType |
Association | |
| original_subject: used to hold the original subject of a relation (or predicate) that an external knowledge source uses before transformation to match the biolink-model specification. |
0..1 String |
Association | |
| original_predicate: used to hold the original relation/predicate that an external knowledge source uses before transformation to match the biolink-model specification. |
0..1 Uriorcurie |
Association | |
| original_object: used to hold the original object of a relation (or predicate) that an external knowledge source uses before transformation to match the biolink-model specification. |
0..1 String |
Association | |
| subject_feature_name: Used to describe a subordinate feature of the associated subject for example, a particular sequence variant of a gene |
0..1 String |
Association | |
| object_feature_name: Used to describe a subordinate feature of the associated object for example, a symptom diagnosis of a disease |
0..1 String |
Association | |
| subject_category: Used to hold the biolink class/category of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
0..1 OntologyClass |
Association | biolink:Gene |
| object_category: Used to hold the biolink class/category of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
0..1 OntologyClass |
Association | biolink:Disease |
| subject_closure: Used to hold the subject closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* String |
Association | |
| object_closure: Used to hold the object closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* String |
Association | ['MONDO:0000167', 'MONDO:0005395'] |
| subject_category_closure: Used to hold the subject category closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* OntologyClass |
Association | ['biolink:Gene", "biolink:NamedThing'] |
| object_category_closure: Used to hold the object category closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* OntologyClass |
Association | ['biolink:Disease", "biolink:NamedThing'] |
| subject_namespace: Used to hold the subject namespace of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
0..1 String |
Association | NCBIGene |
| object_namespace: Used to hold the object namespace of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
0..1 String |
Association | MONDO |
| subject_label_closure: Used to hold the subject label closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* String |
Association | ['BRCA1'] |
| object_label_closure: Used to hold the object label closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* String |
Association | breast cancer, cancer |
| retrieval_source_ids: A list of retrieval sources that served as a source of knowledge expressed in an Edge, or a source of data used to generate this knowledge. |
* RetrievalSource |
Association | |
| p_value: A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone. |
0..1 Float |
Association | |
| adjusted_p_value: The adjusted p-value is the probability of obtaining test results at least as extreme as the results actually observed, under the assumption that the null hypothesis is correct, adjusted for multiple comparisons. P is always italicized and capitalized. The actual P value* should be expressed (P=. 04) rather than expressing a statement of inequality (P<. 05), unless P<. |
0..1 Float |
Association | |
| supporting_text: The segment of text from a document that supports the mined assertion. |
* String |
Association | Here, we report two new cases of rivaroxaban-induced hepatitis. |
| has_supporting_studies: Studies that produced information used as evidence to generate the knowledge expressed in an Association. |
* Study |
Association | |
| update_date: date on which an entity was updated. This can be applied to nodes or edges |
0..1 Date |
Association | |
| has_confidence_score: connects an association to a quantitative (numeric) value that can be interpreted as an indicator of the degree of confidence that a piece of information is true, and accurately reflects the aspect of reality it is about. |
0..1 Float |
Association | |
| elevate_to_prediction: A boolean flag indicating whether a clinical trial finding should be elevated to a prediction. |
0..1 Boolean |
Association | |
| evidence_count: The number of evidence instances that are connected to an association. |
0..1 Integer |
Association | |
| semmed_agreement_count: The number of times this concept has been asserted in the SemMedDB literature database. |
0..1 Integer |
Association | |
| id: A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI |
1 String |
Entity | |
| iri: An IRI for an entity. This is determined by the id using expansion rules. |
0..1 IriType |
Entity | |
| category: Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class. In a neo4j database this MAY correspond to the neo4j label tag. In an RDF database it should be a biolink model class URI. This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values biolink:Protein, biolink:GeneProduct, biolink:MolecularEntity. In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature f may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing} |
* Uriorcurie |
Entity | |
| type: rdf:type of biolink:Association should be fixed at rdf:Statement |
* String |
Entity | |
| name: A human-readable name for an attribute or entity. |
0..1 LabelType |
Entity | |
| description: a human-readable description of an entity |
0..1 NarrativeText |
Entity | |
| has_attribute: connects any entity to an attribute |
* Attribute |
Entity | |
| deprecated: A boolean flag indicating that an entity is no longer considered current or valid. |
0..1 Boolean |
Entity |
LinkML Source
name: anatomical entity has part anatomical entity association
description: A relationship between two anatomical entities where the relationship
is mereological, i.e the two entities are related by parthood, that is, the subject
is has the object entity as a part (the expected predicate is "biolink:has_part"
or suitable predicate slots inheriting from it, i.e., "biolink:has_plasma_membrane_part", "biolink:has_variant_part",
etc.). This includes relationships between cells and cellular components, between
issues and cells, whole organisms and tissues.
from_schema: https://w3id.org/biolink/vocab/
is_a: anatomical entity to anatomical entity association
slot_usage:
subject:
name: subject
description: the whole
range: anatomical entity
object:
name: object
description: the part
range: anatomical entity
predicate:
name: predicate
subproperty_of: has part
defining_slots:
- predicate