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Slot: object_aspect_qualifier

Description: Composes with the core concept to describe new concepts of a different ontological type. e.g. a process in which the core concept participates, a function/activity/role held by the core concept, or a characteristic/quality that inheres in the core concept. The purpose of the aspect slot is to indicate what aspect is being affected in an 'affects' association. This qualifier specifies a change in the object of an association (aka: statement).

Domain: Association
Range: GeneOrGeneProductOrChemicalEntityAspectEnum

Inheritance

Applicable Classes

Name Description Modifies Slot
GeneAffectsChemicalAssociation Describes an effect that a gene or gene product has on a chemical entity (e.g. an impact of on its abundance, activity, localization, processing, transport, etc.) yes
FeatureOrDiseaseQualifiersToEntityMixin Qualifiers for disease or phenotype to entity associations. no
ChemicalGeneSensitivityAssociation Describes a relationship in which a chemical entity affects the sensitivity or susceptibility of a biological system to a gene or gene product (e.g. a chemical that increases or decreases the response to a gene or gene product). This covers 'response to substance' style interactions from sources such as CTD that map to the 'affects sensitivity to' predicate hierarchy, as opposed to the abundance/activity/processing effects covered by ChemicalAffectsGeneAssociation. yes
ChemicalGeneInteractionAssociation describes an interaction between a chemical entity and a gene or gene product. Any biological or chemical effect resulting from such an interaction are out of scope, and covered by the ChemicalAffectsGeneAssociation type (e.g. impact of a chemical on the abundance, activity, structure, etc, of either participant in the interaction) yes
PredicateMapping A deprecated predicate mapping object contains the deprecated predicate and an example of the rewiring that should be done to use a qualified statement in its place. no
GeneRegulatesGeneAssociation Describes a regulatory relationship between two genes or gene products. yes
ChemicalAffectsBiologicalEntityAssociation Describes an effect that a chemical has on a biological entity (e.g. an impact of on its abundance, activity,localization, processing, expression, etc.) yes
MacromolecularMachineHasSubstrateAssociation Describes the relationship between an enzyme (usually a macromolecular complex or gene product) and the molecules it acts on (substrate). The substrate can be a chemical, a polypeptide, or a protein. no
EntityToFeatureOrDiseaseQualifiersMixin Qualifiers for entity to disease or phenotype associations. no
EntityToFeatureOrVariantQualifiersMixin Qualifiers for entity to variant associations. no
GeneToGeneAssociation parent class for different kinds of gene-gene or gene product to gene product relationships. Includes homology and interaction. no
NamedThingAssociatedWithLikelihoodOfNamedThingAssociation An association in which the subject entity is linked to the likelihood of the object entity occurring, manifesting, or being observed. Subject and object may each be qualified by aspect and context, and the association may be further qualified by a population context. yes
EntityToFeatureOrGeneQualifiersMixin Qualifiers for entity to gene associations. no

Example values

Slot Name Value
object_aspect_qualifier stability
object_aspect_qualifier abundance
object_aspect_qualifier expression
object_aspect_qualifier exposure

LinkML Source

name: object aspect qualifier
description: 'Composes with the core concept to describe new concepts of a different
  ontological type. e.g. a process in which the core concept participates, a function/activity/role
  held by the core concept, or a characteristic/quality that inheres in the core concept.  The
  purpose of the aspect slot is to indicate what aspect is being affected in an ''affects''
  association.  This qualifier specifies a change in the object of an association
  (aka: statement).'
examples:
- value: stability
- value: abundance
- value: expression
- value: exposure
in_subset:
- translator_minimal
from_schema: https://w3id.org/biolink/vocab/
is_a: aspect qualifier
domain: association
alias: object_aspect_qualifier
domain_of:
- predicate mapping
- gene to gene association
- named thing associated with likelihood of named thing association
- chemical gene interaction association
- macromolecular machine has substrate association
- gene regulates gene association
- chemical affects biological entity association
- chemical gene sensitivity association
- gene affects chemical association
- entity to feature or disease qualifiers mixin
- entity to feature or variant qualifiers mixin
- entity to feature or gene qualifiers mixin
- feature or disease qualifiers to entity mixin
range: GeneOrGeneProductOrChemicalEntityAspectEnum