Slot: object_aspect_qualifier
Description: Composes with the core concept to describe new concepts of a different ontological type. e.g. a process in which the core concept participates, a function/activity/role held by the core concept, or a characteristic/quality that inheres in the core concept. The purpose of the aspect slot is to indicate what aspect is being affected in an 'affects' association. This qualifier specifies a change in the object of an association (aka: statement).
Domain: Association
Range: GeneOrGeneProductOrChemicalEntityAspectEnum
Inheritance
- association_slot
- qualifier
- aspect_qualifier
- object_aspect_qualifier
- aspect_qualifier
- qualifier
Applicable Classes
| Name | Description | Modifies Slot |
|---|---|---|
| GeneAffectsChemicalAssociation | Describes an effect that a gene or gene product has on a chemical entity (e.g. an impact of on its abundance, activity, localization, processing, transport, etc.) | yes |
| FeatureOrDiseaseQualifiersToEntityMixin | Qualifiers for disease or phenotype to entity associations. | no |
| ChemicalGeneSensitivityAssociation | Describes a relationship in which a chemical entity affects the sensitivity or susceptibility of a biological system to a gene or gene product (e.g. a chemical that increases or decreases the response to a gene or gene product). This covers 'response to substance' style interactions from sources such as CTD that map to the 'affects sensitivity to' predicate hierarchy, as opposed to the abundance/activity/processing effects covered by ChemicalAffectsGeneAssociation. | yes |
| ChemicalGeneInteractionAssociation | describes an interaction between a chemical entity and a gene or gene product. Any biological or chemical effect resulting from such an interaction are out of scope, and covered by the ChemicalAffectsGeneAssociation type (e.g. impact of a chemical on the abundance, activity, structure, etc, of either participant in the interaction) | yes |
| PredicateMapping | A deprecated predicate mapping object contains the deprecated predicate and an example of the rewiring that should be done to use a qualified statement in its place. | no |
| GeneRegulatesGeneAssociation | Describes a regulatory relationship between two genes or gene products. | yes |
| ChemicalAffectsBiologicalEntityAssociation | Describes an effect that a chemical has on a biological entity (e.g. an impact of on its abundance, activity,localization, processing, expression, etc.) | yes |
| MacromolecularMachineHasSubstrateAssociation | Describes the relationship between an enzyme (usually a macromolecular complex or gene product) and the molecules it acts on (substrate). The substrate can be a chemical, a polypeptide, or a protein. | no |
| EntityToFeatureOrDiseaseQualifiersMixin | Qualifiers for entity to disease or phenotype associations. | no |
| EntityToFeatureOrVariantQualifiersMixin | Qualifiers for entity to variant associations. | no |
| GeneToGeneAssociation | parent class for different kinds of gene-gene or gene product to gene product relationships. Includes homology and interaction. | no |
| NamedThingAssociatedWithLikelihoodOfNamedThingAssociation | An association in which the subject entity is linked to the likelihood of the object entity occurring, manifesting, or being observed. Subject and object may each be qualified by aspect and context, and the association may be further qualified by a population context. | yes |
| EntityToFeatureOrGeneQualifiersMixin | Qualifiers for entity to gene associations. | no |
Example values
| Slot Name | Value |
|---|---|
| object_aspect_qualifier | stability |
| object_aspect_qualifier | abundance |
| object_aspect_qualifier | expression |
| object_aspect_qualifier | exposure |
LinkML Source
name: object aspect qualifier
description: 'Composes with the core concept to describe new concepts of a different
ontological type. e.g. a process in which the core concept participates, a function/activity/role
held by the core concept, or a characteristic/quality that inheres in the core concept. The
purpose of the aspect slot is to indicate what aspect is being affected in an ''affects''
association. This qualifier specifies a change in the object of an association
(aka: statement).'
examples:
- value: stability
- value: abundance
- value: expression
- value: exposure
in_subset:
- translator_minimal
from_schema: https://w3id.org/biolink/vocab/
is_a: aspect qualifier
domain: association
alias: object_aspect_qualifier
domain_of:
- predicate mapping
- gene to gene association
- named thing associated with likelihood of named thing association
- chemical gene interaction association
- macromolecular machine has substrate association
- gene regulates gene association
- chemical affects biological entity association
- chemical gene sensitivity association
- gene affects chemical association
- entity to feature or disease qualifiers mixin
- entity to feature or variant qualifiers mixin
- entity to feature or gene qualifiers mixin
- feature or disease qualifiers to entity mixin
range: GeneOrGeneProductOrChemicalEntityAspectEnum