Slot: affects (multivalued)
Description: Describes an entity that has an effect on the state or quality of another existing entity.
Notes: A note on 'affects' vs 'interacts with': These are related but separate relationships. An interaction may or may not involve one interactor exerting an effect on the other. Effects may be mediated by an interaction or may arise without any direct interaction, through a chain of intermediary events. An affects relationship asserts that one entity directly or indirectly exerts a meaningful influence on the activity, state, abundance, function, or properties of another entity. Unlike an interaction, an effect is directional: the subject changes, modulates, perturbs, regulates, or otherwise influences the object, even if no direct physical interaction occurs. Use interacts_with only when the relationship describes an interaction or association without asserting that one entity exerts an effect on the other. Use of the 'affects' predicate implies that the affected entity already exists, unlike predicates such as 'affects likelihood of' and 'prevents' where the effect concerns whether or when something may or may not come into existence.
Notes: A note on 'affects' vs 'interacts with': These are related but separate relationships. An interaction may or may not involve one interactor exerting an effect on the other. Effects may be mediated by an interaction or may arise without any direct interaction, through a chain of intermediary events. An affects relationship asserts that one entity directly or indirectly exerts a meaningful influence on the activity, state, abundance, function, or properties of another entity. Unlike an interaction, an effect is directional: the subject changes, modulates, perturbs, regulates, or otherwise influences the object, even if no direct physical interaction occurs. Use interacts_with only when the relationship describes an interaction or association without asserting that one entity exerts an effect on the other. Use of the 'affects' predicate implies that the affected entity already exists, unlike predicates such as 'affects likelihood of' and 'prevents' where the effect concerns whether or when something may or may not come into existence.
Domain: NamedThing
Range: NamedThing
Inheritance
Annotations
| property | value |
|---|---|
| canonical_predicate | True |
LinkML Source
name: affects
annotations:
canonical_predicate:
tag: canonical_predicate
value: true
description: Describes an entity that has an effect on the state or quality of another
existing entity.
notes:
- 'A note on ''affects'' vs ''interacts with'': These are related but separate relationships.
An interaction may or may not involve one interactor exerting an effect on the other.
Effects may be mediated by an interaction or may arise without any direct interaction,
through a chain of intermediary events. An affects relationship asserts that one
entity directly or indirectly exerts a meaningful influence on the activity, state,
abundance, function, or properties of another entity. Unlike an interaction, an
effect is directional: the subject changes, modulates, perturbs, regulates, or otherwise
influences the object, even if no direct physical interaction occurs. Use interacts_with
only when the relationship describes an interaction or association without asserting
that one entity exerts an effect on the other.'
- Use of the 'affects' predicate implies that the affected entity already exists,
unlike predicates such as 'affects likelihood of' and 'prevents' where the effect
concerns whether or when something may or may not come into existence.
in_subset:
- translator_minimal
from_schema: https://w3id.org/biolink/vocab/
exact_mappings:
- SEMMEDDB:AFFECTS
- DGIdb:affects
related_mappings:
- DRUGBANK:pathway
narrow_mappings:
- CTD:prediction_hypothesis
- GOREL:0001006
- CTD:inferred
- UPHENO:0000001
- RO:0002263
- RO:0002264
- NCIT:R158
- NCIT:R160
- NCIT:R30
- NCIT:R150
- NCIT:R72
- NCIT:R146
- NCIT:R124
- NCIT:R173
- NCIT:R100
- NCIT:R102
- NCIT:R101
- NCIT:R113
- NCIT:R23
- NCIT:R25
- NCIT:gene_mapped_to_disease
- NCIT:R133
- RO:0002343
- RO:0002355
- RO:0002591
- RO:0002592
- RO:0012003
- SNOMED:has_pathological_process
- UBERGRAPH:is_increase_of
- UBERGRAPH:is_decrease_of
is_a: related to at instance level
domain: named thing
inherited: true
range: named thing
multivalued: true