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Slot: subject_direction_qualifier

Description: Composes with the core concept (+ aspect if provided) to describe a change in its direction or degree. This qualifier qualifies the subject of an association (aka: statement).

Domain: Association
Range: DirectionQualifierEnum

Inheritance

Applicable Classes

Name Description Modifies Slot
FeatureOrDiseaseQualifiersToEntityMixin Qualifiers for disease or phenotype to entity associations. no
ChemicalAffectsBiologicalEntityAssociation Describes an effect that a chemical has on a biological entity (e.g. an impact of on its abundance, activity,localization, processing, expression, etc.) yes
GeneToGeneAssociation parent class for different kinds of gene-gene or gene product to gene product relationships. Includes homology and interaction. no
MacromolecularMachineHasSubstrateAssociation Describes the relationship between an enzyme (usually a macromolecular complex or gene product) and the molecules it acts on (substrate). The substrate can be a chemical, a polypeptide, or a protein. no
PredicateMapping A deprecated predicate mapping object contains the deprecated predicate and an example of the rewiring that should be done to use a qualified statement in its place. no
EntityToFeatureOrVariantQualifiersMixin Qualifiers for entity to variant associations. no
EntityToFeatureOrDiseaseQualifiersMixin Qualifiers for entity to disease or phenotype associations. no
EntityToFeatureOrGeneQualifiersMixin Qualifiers for entity to gene associations. no
GeneAffectsChemicalAssociation Describes an effect that a gene or gene product has on a chemical entity (e.g. an impact of on its abundance, activity, localization, processing, transport, etc.) yes

Example values

Slot Name Value
subject_direction_qualifier increased
subject_direction_qualifier downregulated

LinkML Source

name: subject direction qualifier
description: 'Composes with the core concept (+ aspect if provided) to describe a
  change in its direction or degree. This qualifier qualifies the subject of an association
  (aka: statement).'
examples:
- value: increased
- value: downregulated
in_subset:
- translator_minimal
from_schema: https://w3id.org/biolink/vocab/
is_a: direction qualifier
domain: association
alias: subject_direction_qualifier
domain_of:
- predicate mapping
- gene to gene association
- macromolecular machine has substrate association
- chemical affects biological entity association
- gene affects chemical association
- entity to feature or disease qualifiers mixin
- entity to feature or variant qualifiers mixin
- entity to feature or gene qualifiers mixin
- feature or disease qualifiers to entity mixin
range: DirectionQualifierEnum