Slot: pIC50
Description: Negative base 10 logarithm of the the inhibitory concentration 50% (IC50) measures the concentration needed to block or inhibit a biological response.
Domain: NamedThing
Range: QuantityValue
Inheritance
- node_property
- pIC50
Applicable Classes
| Name | Description | Modifies Slot |
|---|---|---|
| ProteinLigandAssayResult | The type of study result describing the strength of interaction affinity - or enzymatic interaction - between a ligand and a target protein. Measured binding or enzymatic assay values are generally stated as the negative base 10 logarithm of the raw measurements. For instance (i.e., in a molecular interaction database like BindingDb) if a ligand inhibits a target protein with a pIC50 of 8.6, then the affinity parameter is pIC50 and the affinity value is 8.6. | no |
LinkML Source
name: pIC50
description: Negative base 10 logarithm of the the inhibitory concentration 50% (IC50)
measures the concentration needed to block or inhibit a biological response.
from_schema: https://w3id.org/biolink/vocab/
is_a: node property
domain: named thing
domain_of:
- protein ligand assay result
range: quantity value