Slot: pEC50

Description: Negative base 10 logarithm of the molar concentration of a chemical that produces a 50% excitation of a function

Domain: NamedThing
Range: QuantityValue

Inheritance

• node_property
  • pEC50

Applicable Classes

Name	Description	Modifies Slot
ProteinLigandAssayResult	The type of study result describing the strength of interaction affinity - or enzymatic interaction - between a ligand and a target protein. Measured binding or enzymatic assay values are generally stated as the negative base 10 logarithm of the raw measurements. For instance (i.e., in a molecular interaction database like BindingDb) if a ligand inhibits a target protein with a pIC50 of 8.6, then the affinity parameter is pIC50 and the affinity value is 8.6.	no

LinkML Source

name: pEC50
description: Negative base 10 logarithm of the molar concentration of a chemical that
  produces a 50% excitation of a function
from_schema: https://w3id.org/biolink/vocab/
is_a: node property
domain: named thing
domain_of:
- protein ligand assay result
range: quantity value