Slot: applied_to_treat (multivalued)
Description: Holds between an substance, procedure, or activity and a medical condition, and reports that the substance, procedure, or activity was actually taken by one or more patients with the intent of treating the condition.
Aliases: administered to treat, used to treat, given to treat
Notes: This predicate is used simply to report observations of use in the real world, and is agnostic to whether the treatment is approved for or might be effective in treating the condition. The treatment could be taken by a patient on their own accord or prescribed by a clinician, as an off-label or an approved intervention. In practice, it would be used to represent records/statements from patient self-reporting sources like FAERS / AEOLUS where patients directly report the condition for which they took a drug, or statements from a database cataloging instances of off-label prescription of drugs for specific conditions (e.g. here, here, here).
Aliases: administered to treat, used to treat, given to treat
Notes: This predicate is used simply to report observations of use in the real world, and is agnostic to whether the treatment is approved for or might be effective in treating the condition. The treatment could be taken by a patient on their own accord or prescribed by a clinician, as an off-label or an approved intervention. In practice, it would be used to represent records/statements from patient self-reporting sources like FAERS / AEOLUS where patients directly report the condition for which they took a drug, or statements from a database cataloging instances of off-label prescription of drugs for specific conditions (e.g. here, here, here).
Domain: ChemicalOrDrugOrTreatment
Range: DiseaseOrPhenotypicFeature
Inheritance
- related_to
- related_to_at_instance_level
- applied_to_treat [ treats_or_applied_or_studied_to_treat]
- related_to_at_instance_level
Annotations
| property | value |
|---|---|
| canonical_predicate | True |
LinkML Source
name: applied to treat
annotations:
canonical_predicate:
tag: canonical_predicate
value: true
description: Holds between an substance, procedure, or activity and a medical condition,
and reports that the substance, procedure, or activity was actually taken by one
or more patients with the intent of treating the condition.
notes:
- This predicate is used simply to report observations of use in the real world, and
is agnostic to whether the treatment is approved for or might be effective in treating
the condition. The treatment could be taken by a patient on their own accord or
prescribed by a clinician, as an off-label or an approved intervention. In practice,
it would be used to represent records/statements from patient self-reporting sources
like FAERS / AEOLUS where patients directly report the condition for which they
took a drug, or statements from a database cataloging instances of off-label prescription
of drugs for specific conditions (e.g. here, here, here).
in_subset:
- translator_minimal
from_schema: https://w3id.org/biolink/biolink-model
aliases:
- administered to treat
- used to treat
- given to treat
broad_mappings:
- SEMMEDDB:ADMINISTERED_TO
is_a: related to at instance level
mixins:
- treats or applied or studied to treat
domain: chemical or drug or treatment
multivalued: true
inherited: true
alias: applied_to_treat
range: disease or phenotypic feature