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Slot: treats_or_applied_or_studied_to_treat (multivalued)

Description: Holds between an substance, procedure, or activity and a medical condition (disease or phenotypic feature), and states that the substance, procedure, or activity is able to treat the condition, has been observed to be taken/prescribed in practice with the intent of treating the condition, or has been interrogated in a scientific study that hypothesized an ability to treat the condition (in humans or other biological systems/organisms).

Notes: This predicate is helpful both as a grouping predicate to aid in searching for broader senses of treating a condition, and as a catch-all for representing sources that are not clear about the sense of treats that is being reported. For example, text-mined statements concerning treatments for disease are based on sentences that can report treatment in any of these different senses and thus require a broader predicate such as this to safely report statement semantics.

Domain: ChemicalOrDrugOrTreatment
Range: DiseaseOrPhenotypicFeature

Inheritance

Mixin Usage

mixed into description range domain
studied_to_treat Holds between an substance, procedure, or activity and a medical condition, and reports that one or more scientific study has been performed to specifically test the potential of the substance, procedure, or activity to treat the medical condition (i.e. to ameliorate, stabilize, or cure the condition, or to delay, prevent, or reduce the risk of it manifesting in the first place). disease or phenotypic feature
in_clinical_trials_for Holds between an intervention and a medical condition, and reports that a clinical trial is being or has been performed in human patients to test the potential of the intervention to treat the medical condition (e.g. to ameliorate, stabilize, or cure the condition, or to delay, prevent, or reduce the risk of it manifesting in the first place). disease or phenotypic feature
in_preclinical_trials_for Holds between an substance, procedure, or activity and a medical condition, and reports that a pre-clinical study has been performed specifically to test the potential of the substance, procedure, or activity to treat the medical condition (i.e. to ameliorate, stabilize, or cure the condition, or to delay, prevent, or reduce the risk of it manifesting in the first place). disease or phenotypic feature
beneficial_in_models_for Holds between an substance, procedure, or activity and a medical condition, and reports that the substance, procedure, or activity has been shown to be effective in alleviating, preventing, or delaying symptoms/ phenotypes associated with a disease, in a model system for that disease (e.g. a mouse, fly, cell line, etc). disease or phenotypic feature
applied_to_treat Holds between an substance, procedure, or activity and a medical condition, and reports that the substance, procedure, or activity was actually taken by one or more patients with the intent of treating the condition. disease or phenotypic feature

Annotations

property value
canonical_predicate True

LinkML Source

name: treats or applied or studied to treat
annotations:
  canonical_predicate:
    tag: canonical_predicate
    value: true
description: Holds between an substance, procedure, or activity and a medical condition
  (disease or phenotypic feature), and states that the substance, procedure, or activity
  is able to treat the condition, has been observed to be taken/prescribed in practice
  with the intent of treating the condition, or has been interrogated in a scientific
  study that hypothesized an ability to treat the condition (in humans or other biological
  systems/organisms).
notes:
- This predicate is helpful both as a grouping predicate to aid in searching for broader
  senses of treating a condition, and as a catch-all for representing sources that
  are not clear about the sense of treats that is being reported. For example, text-mined
  statements concerning treatments for disease are based on sentences that can report
  treatment in any of these different senses and thus require a broader predicate
  such as this to safely report statement semantics.
in_subset:
- translator_minimal
from_schema: https://w3id.org/biolink/biolink-model
exact_mappings:
- SEMMEDDB:TREATS
is_a: related to at instance level
mixin: true
domain: chemical or drug or treatment
inherited: true
alias: treats_or_applied_or_studied_to_treat
range: disease or phenotypic feature
multivalued: true