A (possibly time bounded) incidence of a feature of the environment of an organism that influences one or more phenotypic features of that organism, potentially mediated by genes
- BehavioralExposure (mixin) - A behavioral exposure is a factor relating to behavior impacting an individual.
- BioticExposure (mixin) - An external biotic exposure is an intake of (sometimes pathological) biological organisms (including viruses).
- ChemicalExposure (mixin) - A chemical exposure is an intake of a particular chemical entity.
- DiseaseOrPhenotypicFeatureExposure (mixin) - A disease or phenotypic feature state, when viewed as an exposure, represents an precondition, leading to or influencing an outcome, e.g. HIV predisposing an individual to infections; a relative deficiency of skin pigmentation predisposing an individual to skin cancer.
- DrugExposure (mixin) - A drug exposure is an intake of a particular drug.
- EnvironmentalExposure (mixin) - A environmental exposure is a factor relating to abiotic processes in the environment including sunlight (UV-B), atmospheric (heat, cold, general pollution) and water-born contaminants.
- GenomicBackgroundExposure (mixin) - A genomic background exposure is where an individual’s specific genomic background of genes, sequence variants or other pre-existing genomic conditions constitute a kind of ‘exposure’ to the organism, leading to or influencing an outcome.
- GeographicExposure (mixin) - A geographic exposure is a factor relating to geographic proximity to some impactful entity.
- PathologicalAnatomicalExposure (mixin) - An abnormal anatomical structure, when viewed as an exposure, representing an precondition, leading to or influencing an outcome, e.g. thrombosis leading to an ischemic disease outcome.
- PathologicalProcessExposure (mixin) - A pathological process, when viewed as an exposure, representing a precondition, leading to or influencing an outcome, e.g. autoimmunity leading to disease.
- SocioeconomicExposure (mixin) - A socioeconomic exposure is a factor relating to social and financial status of an affected individual (e.g. poverty).
- Treatment (mixin) - A treatment is targeted at a disease or phenotype and may involve multiple drug ‘exposures’, medical devices and/or procedures
- EntityToExposureEventAssociationMixin entity to exposure event association mixin➞object 1..1 ExposureEvent
- ExposureEventToPhenotypicFeatureAssociation exposure event to phenotypic feature association➞subject 1..1 ExposureEvent