Class: Drug

A substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease

URI: biolink:Drug

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Identifier prefixes

• ncats.drug
• RXCUI
• NDC
• UMLS

Parents

• is_a: MolecularMixture - A molecular mixture is a chemical mixture composed of two or more molecular entities with known concentration and stoichiometry.

Uses Mixins

• mixin: ChemicalOrDrugOrTreatment
• mixin: OntologyClass - a concept or class in an ontology, vocabulary or thesaurus. Note that nodes in a biolink compatible KG can be considered both instances of biolink classes, and OWL classes in their own right. In general you should not need to use this class directly. Instead, use the appropriate biolink class. For example, for the GO concept of endocytosis (GO:0006897), use bl:BiologicalProcess as the type.

Referenced by class

• DrugToEntityAssociationMixin subject _1..1 Drug
• DiseaseOrPhenotypicFeature has contraindication _0..* Drug
• NamedThing has drug _0..* Drug
• MolecularEntity is active ingredient of _0..* Drug
• MolecularEntity is excipient of _0..* Drug

Attributes

Inherited from chemical entity:

• trade name _0..1
  • Range: ChemicalEntity
• available from _0..*
  • Range: DrugAvailabilityEnum
• max tolerated dose _0..1
  • Description: The highest dose of a drug or treatment that does not cause unacceptable side effects. The maximum tolerated dose is determined in clinical trials by testing increasing doses on different groups of people until the highest dose with acceptable side effects is found. Also called MTD.
  • Range: String
• is toxic _0..1
  • Range: Boolean
• has chemical role _0..*
  • Description: A role is particular behaviour which a chemical entity may exhibit.
  • Range: ChemicalRole

Inherited from chemical mixture:

• is supplement _0..1
  • Range: ChemicalMixture
• highest FDA approval status _0..1
  • Description: Should be the highest level of FDA approval this chemical entity or device has, regardless of which disease, condition or phenotype it is currently being reviewed to treat. For specific levels of FDA approval for a specific condition, disease, phenotype, etc., see the association slot, ‘FDA approval status.’
  • Range: String
• drug regulatory status world wide _0..1
  • Description: An agglomeration of drug regulatory status worldwide. Not specific to FDA.
  • Range: String
• routes of delivery _0..*
  • Description: the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals.
  • Range: DrugDeliveryEnum

Inherited from entity:

• id _1..1
  • Description: A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI
  • Range: String
  • in subsets: (translator_minimal)
• iri _0..1
  • Description: An IRI for an entity. This is determined by the id using expansion rules.
  • Range: IriType
  • in subsets: (translator_minimal,samples)
• category _0..*
  • Description: Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class.
• In a neo4j database this MAY correspond to the neo4j label tag.
• In an RDF database it should be a biolink model class URI. This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values biolink:Protein, biolink:GeneProduct, biolink:MolecularEntity, … In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature f may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing}
  • Range: CategoryType
  • in subsets: (translator_minimal)
• type _0..*
  • Range: String
• description _0..1
  • Description: a human-readable description of an entity
  • Range: NarrativeText
  • in subsets: (translator_minimal)
• has attribute _0..*
  • Description: connects any entity to an attribute
  • Range: Attribute
  • in subsets: (samples)

Inherited from gene product mixin:

• xref _0..*
  • Description: Alternate CURIEs for a thing
  • Range: Uriorcurie
  • in subsets: (translator_minimal)

Inherited from macromolecular machine mixin:

• name _0..1
  • Description: A human-readable name for an attribute or entity.
  • Range: LabelType
  • in subsets: (translator_minimal,samples)

Inherited from named thing:

• provided by _0..*
  • Description: The value in this node property represents the knowledge provider that created or assembled the node and all of its attributes. Used internally to represent how a particular node made its way into a knowledge provider or graph.
  • Range: String
• category _0..*
  • Description: Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class.
• In a neo4j database this MAY correspond to the neo4j label tag.
• In an RDF database it should be a biolink model class URI. This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values biolink:Protein, biolink:GeneProduct, biolink:MolecularEntity, … In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature f may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing}
  • Range: CategoryType
  • in subsets: (translator_minimal)

Other properties