Class: DiseaseOrPhenotypicFeature

Either one of a disease or an individual phenotypic feature. Some knowledge resources such as Monarch treat these as distinct, others such as MESH conflate.

URI: biolink:DiseaseOrPhenotypicFeature

---

---

Parents

• is_a: BiologicalEntity

Uses Mixins

• mixin: ThingWithTaxon - A mixin that can be used on any entity that can be taxonomically classified. This includes individual organisms; genes, their products and other molecular entities; body parts; biological processes

Children

• Disease
• DiseaseOrPhenotypicFeatureExposure - A disease or phenotypic feature state, when viewed as an exposure, represents an precondition, leading to or influencing an outcome, e.g. HIV predisposing an individual to infections; a relative deficiency of skin pigmentation predisposing an individual to skin cancer.
• DiseaseOrPhenotypicFeatureOutcome - Physiological outcomes resulting from an exposure event which is the manifestation of a disease or other characteristic phenotype.
• PhenotypicFeature

Referenced by class

• BiologicalEntity ameliorates _0..* DiseaseOrPhenotypicFeature
• Treatment approved to treat _0..* DiseaseOrPhenotypicFeature
• MolecularEntity biomarker for _0..* DiseaseOrPhenotypicFeature
• Drug causes adverse event _0..* DiseaseOrPhenotypicFeature
• CellLineToDiseaseOrPhenotypicFeatureAssociation cell line to disease or phenotypic feature association➞subject _REQ DiseaseOrPhenotypicFeature
• ChemicalToDiseaseOrPhenotypicFeatureAssociation chemical to disease or phenotypic feature association➞object _REQ DiseaseOrPhenotypicFeature
• Drug contraindicated for _0..* DiseaseOrPhenotypicFeature
• DiseaseOrPhenotypicFeatureToEntityAssociationMixin disease or phenotypic feature to entity association mixin➞subject _REQ DiseaseOrPhenotypicFeature
• EntityToDiseaseOrPhenotypicFeatureAssociationMixin entity to disease or phenotypic feature association mixin➞object _REQ DiseaseOrPhenotypicFeature
• BiologicalEntity exacerbates _0..* DiseaseOrPhenotypicFeature
• Gene gene associated with condition _0..* DiseaseOrPhenotypicFeature
• Association phenotypic state _OPT DiseaseOrPhenotypicFeature
• Treatment treats _0..* DiseaseOrPhenotypicFeature

Attributes

Inherited from entity:

• id _REQ
  • Description: A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI
  • range: String
  • in subsets: (translator_minimal)
• iri _OPT
  • Description: An IRI for an entity. This is determined by the id using expansion rules.
  • range: IriType
  • in subsets: (translator_minimal,samples)
• category _1..*
  • Description: Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class.
• In a neo4j database this MAY correspond to the neo4j label tag.
• In an RDF database it should be a biolink model class URI. This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values bl:Protein, bl:GeneProduct, bl:MolecularEntity, … In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature f may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {bl:GenomicEntity, bl:MolecularEntity, bl:NamedThing}
  • range: CategoryType
  • in subsets: (translator_minimal)
• type _OPT
  • range: String
• description _OPT
  • Description: a human-readable description of an entity
  • range: NarrativeText
  • in subsets: (translator_minimal)
• source _OPT
  • Description: a lightweight analog to the association class ‘has provider’ slot, which is the string name, or the authoritative (i.e. database) namespace, designating the origin of the entity to which the slot belongs.
  • range: LabelType
  • in subsets: (translator_minimal)
• provided by _0..*
  • Description: connects an association to the agent (person, organization or group) that provided it
  • range: Agent
• has attribute _0..*
  • Description: connects any entity to an attribute
  • range: Attribute
  • in subsets: (samples)

Inherited from macromolecular machine mixin:

• macromolecular machine mixin➞name _OPT
  • Description: genes are typically designated by a short symbol and a full name. We map the symbol to the default display name and use an additional slot for full name
  • range: SymbolType

Inherited from named thing:

• named thing➞category _1..*
  • range: NamedThing

Inherited from thing with taxon:

• in taxon _0..*
  • Description: connects an entity to its taxonomic classification. Only certain kinds of entities can be taxonomically classified; see ‘thing with taxon’
  • range: OrganismTaxon
  • in subsets: (translator_minimal)

Other properties