Slot: contraindicated_in (multivalued)
Description: Holds between a substance, procedure, or activity and a medical condition or circumstance, where an authority has established that the substance, procedure, or activity should not be applied as an intervention in patients with the condition or circumstance because it can result in detrimental outcomes.
Notes: This predicate relates the intervention with a specific disease, phenotype, or other medical circumstance that puts patients at high risk for detrimental outcomes. This may be a different condition from the one that the drug would be used to treat (e.g. pseudoephedrine is contraindicated in people with high-blood pressure as a treatment for nasal congestion), a biological state (e.g. isotretinoin is contraindicated in people who are pregnant as a treatment for acne), or being on a different medication (e.g. aspirin is contraindicated in people taking warfarin as a preventative treatment for stroke).
Notes: This predicate relates the intervention with a specific disease, phenotype, or other medical circumstance that puts patients at high risk for detrimental outcomes. This may be a different condition from the one that the drug would be used to treat (e.g. pseudoephedrine is contraindicated in people with high-blood pressure as a treatment for nasal congestion), a biological state (e.g. isotretinoin is contraindicated in people who are pregnant as a treatment for acne), or being on a different medication (e.g. aspirin is contraindicated in people taking warfarin as a preventative treatment for stroke).
Domain: ChemicalOrDrugOrTreatment
Range: BiologicalEntity
Inheritance
- related_to
- related_to_at_instance_level
- contraindicated_in
- related_to_at_instance_level
Annotations
| property | value |
|---|---|
| canonical_predicate | True |
LinkML Source
name: contraindicated in
annotations:
canonical_predicate:
tag: canonical_predicate
value: true
opposite_of:
tag: opposite_of
value: treats
description: Holds between a substance, procedure, or activity and a medical condition
or circumstance, where an authority has established that the substance, procedure,
or activity should not be applied as an intervention in patients with the condition
or circumstance because it can result in detrimental outcomes.
notes:
- This predicate relates the intervention with a specific disease, phenotype, or other
medical circumstance that puts patients at high risk for detrimental outcomes. This
may be a different condition from the one that the drug would be used to treat (e.g.
pseudoephedrine is contraindicated in people with high-blood pressure as a treatment
for nasal congestion), a biological state (e.g. isotretinoin is contraindicated
in people who are pregnant as a treatment for acne), or being on a different medication
(e.g. aspirin is contraindicated in people taking warfarin as a preventative treatment
for stroke).
from_schema: https://w3id.org/biolink/biolink-model
exact_mappings:
- NCIT:C37933
is_a: related to at instance level
domain: chemical or drug or treatment
inherited: true
alias: contraindicated_in
range: biological entity
multivalued: true