Slot: allelic_requirement
Description: The allele configuration of a particular gene or variant required for the expression of a disease or phenotype in a specific patient or instance.
Domain: Association
Range: String
Inheritance
- association_slot
- allelic_requirement
Applicable Classes
Name | Description | Modifies Slot |
---|---|---|
GeneToDiseaseOrPhenotypicFeatureAssociation | None | no |
LinkML Source
name: allelic requirement
description: The allele configuration of a particular gene or variant required for
the expression of a disease or phenotype in a specific patient or instance.
comments:
- This edge property may be used by associations between Genes or SequenceVariants
and DiseaseOrPhenotypicFeatures to provide the inheritance pattern and genetic context
of the relationship. Terms from the HP mode of inheritance sub-ontology (HP:0000005)
should be used in the value of this slot. This slot differs from the predicate "has_mode_of_inheritance",
in that the predicate is used to link a disease or phenotype with its general inheritance
pattern (how it is typically transmitted from one generation to the next, regardless
of the specific genetic variant that is present in an individual or instance).
from_schema: https://w3id.org/biolink/biolink-model
is_a: association slot
domain: association
alias: allelic_requirement
domain_of:
- gene to disease or phenotypic feature association
range: string
pattern: ^HP:\d{7}$