Enum: ResearchPhaseEnum

Permissible Values

Value	Meaning	Description
pre_clinical_research_phase	None	Biolink 'pre_clinical_research' is the union of both the FDA discovery and development phase and FDA preclinical research phase. Discovery involves researchers finding new possibilities for medication through testing molecular compounds, noting unexpected effects from existing treatments, or the creation of new technology that allows novel ways of targeting medical products to sites in the body. Drug development occurs after researchers identify potential compounds for experiments Preclinical Research Phase. Once researchers have examined the possibilities a new drug may contain, they must do preliminary research to determine its potential for harm (toxicity). This is categorized as preclinical research and can be one of two types: in vitro or in vivo.
clinical_trial_phase	None	Clinical research involves trials of the drug on people, and it is one of the most involved stages in the drug development and approval process. Clinical trials must answer specific questions and follow a protocol determined by the drug researcher or manufacturer.
clinical_trial_phase_1	None	In the FDA Clinical Trial Phase, the Clinical Trial Phase 1 involves 20 – 100 study participants and lasts several months. This phase is used to determine the safety and dosage of the drug, and about 70% of these drugs move on to the next clinical research phase.
clinical_trial_phase_2	None	In the FDA Clinical Trial Phase, the Clinical Trial Phase 2 involves up to several hundred people, who must have the disease or condition the drug supposes to treat. This phase can last from a few months to two years, and its purpose is to monitor the efficacy of the drug, as well as note side effects that may occur.
clinical_trial_phase_3	None	In the FDA Clinical Trial Phase, the Clinical Trial Phase 3 involves 300 – 3000 volunteers and can last up to four years. It is used to continue monitoring the efficacy of the drug, as well as exploring any longer-term adverse reactions.
clinical_trial_phase_4	None	In the FDA Clinical Trial Phase, the Clinical Trial Phase 4 involves several thousands of volunteers who have the disease or condition and continues to monitor safety and efficacy. If a drug passes this phase, it goes on to FDA review.
not_provided	None	None

Slots constrained by this enum

Name
max_research_phase

LinkML Source

name: ResearchPhaseEnum
from_schema: https://w3id.org/biolink/biolink-model
permissible_values:
  pre_clinical_research_phase:
    text: pre_clinical_research_phase
    description: 'Biolink ''pre_clinical_research'' is the union of both the `FDA
      discovery and development phase` and `FDA preclinical research phase`. Discovery
      involves researchers finding new possibilities for medication through testing
      molecular compounds, noting unexpected effects from existing treatments, or
      the creation of new technology that allows novel ways of targeting medical products
      to sites in the body. Drug development occurs after researchers identify potential
      compounds for experiments Preclinical Research Phase. Once researchers have
      examined the possibilities a new drug may contain, they must do preliminary
      research to determine its potential for harm (toxicity). This is categorized
      as preclinical research and can be one of two types: in vitro or in vivo.'
    notes:
    - DrugBank calls this 'experimental'.
  clinical_trial_phase:
    text: clinical_trial_phase
    description: Clinical research involves trials of the drug on people, and it is
      one of the most involved stages in the drug development and approval process.
      Clinical trials must answer specific questions and follow a protocol determined
      by the drug researcher or manufacturer.
  clinical_trial_phase_1:
    text: clinical_trial_phase_1
    description: In the FDA Clinical Trial Phase, the Clinical Trial Phase 1 involves
      20 – 100 study participants and lasts several months. This phase is used to
      determine the safety and dosage of the drug, and about 70% of these drugs move
      on to the next clinical research phase.
    is_a: clinical_trial_phase
  clinical_trial_phase_2:
    text: clinical_trial_phase_2
    description: In the FDA Clinical Trial Phase, the Clinical Trial Phase 2 involves
      up to several hundred people, who must have the disease or condition the drug
      supposes to treat. This phase can last from a few months to two years, and its
      purpose is to monitor the efficacy of the drug, as well as note side effects
      that may occur.
    is_a: clinical_trial_phase
  clinical_trial_phase_3:
    text: clinical_trial_phase_3
    description: In the FDA Clinical Trial Phase, the Clinical Trial Phase 3 involves
      300 – 3000 volunteers and can last up to four years. It is used to continue
      monitoring the efficacy of the drug, as well as exploring any longer-term adverse
      reactions.
    is_a: clinical_trial_phase
  clinical_trial_phase_4:
    text: clinical_trial_phase_4
    description: In the FDA Clinical Trial Phase, the Clinical Trial Phase 4 involves
      several thousands of volunteers who have the disease or condition and continues
      to monitor safety and efficacy. If a drug passes this phase, it goes on to FDA
      review.
    is_a: clinical_trial_phase
  not_provided:
    text: not_provided