Class: ReactionToCatalystAssociation
classDiagram
class ReactionToCatalystAssociation
ReactionToParticipantAssociation <|-- ReactionToCatalystAssociation
ReactionToCatalystAssociation : adjusted_p_value
ReactionToCatalystAssociation : agent_type
ReactionToCatalystAssociation --|> AgentTypeEnum : agent_type
ReactionToCatalystAssociation : aggregator_knowledge_source
ReactionToCatalystAssociation : category
ReactionToCatalystAssociation : deprecated
ReactionToCatalystAssociation : description
ReactionToCatalystAssociation : has_attribute
ReactionToCatalystAssociation --|> Attribute : has_attribute
ReactionToCatalystAssociation : has_evidence
ReactionToCatalystAssociation --|> EvidenceType : has_evidence
ReactionToCatalystAssociation : has_supporting_studies
ReactionToCatalystAssociation --|> Study : has_supporting_studies
ReactionToCatalystAssociation : id
ReactionToCatalystAssociation : iri
ReactionToCatalystAssociation : knowledge_level
ReactionToCatalystAssociation --|> KnowledgeLevelEnum : knowledge_level
ReactionToCatalystAssociation : knowledge_source
ReactionToCatalystAssociation : name
ReactionToCatalystAssociation : negated
ReactionToCatalystAssociation : object
ReactionToCatalystAssociation --|> GeneOrGeneProduct : object
ReactionToCatalystAssociation : object_category
ReactionToCatalystAssociation --|> OntologyClass : object_category
ReactionToCatalystAssociation : object_category_closure
ReactionToCatalystAssociation --|> OntologyClass : object_category_closure
ReactionToCatalystAssociation : object_closure
ReactionToCatalystAssociation : object_label_closure
ReactionToCatalystAssociation : object_namespace
ReactionToCatalystAssociation : original_object
ReactionToCatalystAssociation : original_predicate
ReactionToCatalystAssociation : original_subject
ReactionToCatalystAssociation : p_value
ReactionToCatalystAssociation : predicate
ReactionToCatalystAssociation : primary_knowledge_source
ReactionToCatalystAssociation : publications
ReactionToCatalystAssociation --|> Publication : publications
ReactionToCatalystAssociation : qualifier
ReactionToCatalystAssociation : qualifiers
ReactionToCatalystAssociation --|> OntologyClass : qualifiers
ReactionToCatalystAssociation : reaction_direction
ReactionToCatalystAssociation --|> ReactionDirectionEnum : reaction_direction
ReactionToCatalystAssociation : reaction_side
ReactionToCatalystAssociation --|> ReactionSideEnum : reaction_side
ReactionToCatalystAssociation : retrieval_source_ids
ReactionToCatalystAssociation --|> RetrievalSource : retrieval_source_ids
ReactionToCatalystAssociation : stoichiometry
ReactionToCatalystAssociation : subject
ReactionToCatalystAssociation --|> MolecularEntity : subject
ReactionToCatalystAssociation : subject_category
ReactionToCatalystAssociation --|> OntologyClass : subject_category
ReactionToCatalystAssociation : subject_category_closure
ReactionToCatalystAssociation --|> OntologyClass : subject_category_closure
ReactionToCatalystAssociation : subject_closure
ReactionToCatalystAssociation : subject_label_closure
ReactionToCatalystAssociation : subject_namespace
ReactionToCatalystAssociation : timepoint
ReactionToCatalystAssociation : type
Inheritance
- Entity
- Association
- ChemicalToChemicalAssociation [ ChemicalToEntityAssociationMixin]
- ReactionToParticipantAssociation
- ReactionToCatalystAssociation
- ReactionToParticipantAssociation
- ChemicalToChemicalAssociation [ ChemicalToEntityAssociationMixin]
- Association
Slots
Name | Cardinality and Range | Inheritance | Examples |
---|---|---|---|
stoichiometry: the relationship between the relative quantities of substances taking part in a reaction or forming a compound, typically a ratio of whole integers. |
0..1 Integer |
ReactionToParticipantAssociation | |
reaction_direction: the direction of a reaction as constrained by the direction enum (ie: left_to_right, neutral, etc.) |
0..1 ReactionDirectionEnum |
ReactionToParticipantAssociation | |
reaction_side: the side of a reaction being modeled (ie: left or right) |
0..1 ReactionSideEnum |
ReactionToParticipantAssociation | |
subject: the chemical entity or entity that is an interactor |
1 MolecularEntity |
ChemicalEntityToEntityAssociationMixin, ChemicalToChemicalAssociation, ChemicalToEntityAssociationMixin, Association | |
predicate: A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. |
1 PredicateType |
ChemicalEntityToEntityAssociationMixin, ChemicalToChemicalAssociation, ChemicalToEntityAssociationMixin, Association | |
object: the chemical element that is the target of the statement |
1 GeneOrGeneProduct |
ChemicalEntityToEntityAssociationMixin, ChemicalToChemicalAssociation, ChemicalToEntityAssociationMixin, Association | |
negated: if set to true, then the association is negated i.e. is not true |
0..1 Boolean |
Association | |
qualifier: grouping slot for all qualifiers on an edge. useful for testing compliance with association classes |
0..1 String |
Association | |
qualifiers: connects an association to qualifiers that modify or qualify the meaning of that association |
* OntologyClass |
Association | |
publications: One or more publications that report the statement expressed in an Association, or provide information used as evidence supporting this statement. |
* Publication |
Association | |
has_evidence: connects an association to an instance of supporting evidence |
* EvidenceType |
Association | |
knowledge_source: An Information Resource from which the knowledge expressed in an Association was retrieved, directly or indirectly. This can be any resource through which the knowledge passed on its way to its currently serialized form. In practice, implementers should use one of the more specific subtypes of this generic property. |
0..1 String |
Association | |
primary_knowledge_source: The most upstream source of the knowledge expressed in an Association that an implementer can identify. Performing a rigorous analysis of upstream data providers is expected; every effort is made to catalog the most upstream source of data in this property. Only one data source should be declared primary in any association. "aggregator knowledge source" can be used to capture non-primary sources. |
0..1 String |
Association | |
aggregator_knowledge_source: An intermediate aggregator resource from which knowledge expressed in an Association was retrieved downstream of the original source, on its path to its current serialized form. |
* String |
Association | |
knowledge_level: Describes the level of knowledge expressed in a statement, based on the reasoning or analysis methods used to generate the statement, or the scope or specificity of what the statement expresses to be true. |
1 KnowledgeLevelEnum |
Association | knowledge_assertion, prediction, statistical_association |
agent_type: Describes the high-level category of agent who originally generated a statement of knowledge or other type of information. |
1 AgentTypeEnum |
Association | manual_agent, automated_agent, computational_model, text_mining_agent |
timepoint: a point in time |
0..1 TimeType |
Association | |
original_subject: used to hold the original subject of a relation (or predicate) that an external knowledge source uses before transformation to match the biolink-model specification. |
0..1 String |
Association | |
original_predicate: used to hold the original relation/predicate that an external knowledge source uses before transformation to match the biolink-model specification. |
0..1 Uriorcurie |
Association | |
original_object: used to hold the original object of a relation (or predicate) that an external knowledge source uses before transformation to match the biolink-model specification. |
0..1 String |
Association | |
subject_category: Used to hold the biolink class/category of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
0..1 OntologyClass |
Association | biolink:Gene |
object_category: Used to hold the biolink class/category of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
0..1 OntologyClass |
Association | biolink:Disease |
subject_closure: Used to hold the subject closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* String |
Association | |
object_closure: Used to hold the object closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* String |
Association | ['MONDO:0000167', 'MONDO:0005395'] |
subject_category_closure: Used to hold the subject category closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* OntologyClass |
Association | ['biolink:Gene", "biolink:NamedThing'] |
object_category_closure: Used to hold the object category closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* OntologyClass |
Association | ['biolink:Disease", "biolink:NamedThing'] |
subject_namespace: Used to hold the subject namespace of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
0..1 String |
Association | NCBIGene |
object_namespace: Used to hold the object namespace of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
0..1 String |
Association | MONDO |
subject_label_closure: Used to hold the subject label closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* String |
Association | ['BRACA1'] |
object_label_closure: Used to hold the object label closure of an association. This is a denormalized field used primarily in the SQL serialization of a knowledge graph via KGX. |
* String |
Association | breast cancer, cancer |
retrieval_source_ids: A list of retrieval sources that served as a source of knowledge expressed in an Edge, or a source of data used to generate this knowledge. |
* RetrievalSource |
Association | |
p_value: A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone. |
0..1 Float |
Association | |
adjusted_p_value: The adjusted p-value is the probability of obtaining test results at least as extreme as the results actually observed, under the assumption that the null hypothesis is correct, adjusted for multiple comparisons. P is always italicized and capitalized. The actual P value* should be expressed (P=. 04) rather than expressing a statement of inequality (P<. 05), unless P<. |
0..1 Float |
Association | |
has_supporting_studies: A study that produced information used as evidence to generate the knowledge expressed in an Association. |
* Study |
Association | |
id: A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI |
1 String |
Entity | |
iri: An IRI for an entity. This is determined by the id using expansion rules. |
0..1 IriType |
Entity | |
category: Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class. In a neo4j database this MAY correspond to the neo4j label tag. In an RDF database it should be a biolink model class URI. This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values biolink:Protein , biolink:GeneProduct , biolink:MolecularEntity . In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature f may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing} |
* Uriorcurie |
Entity | |
type: rdf:type of biolink:Association should be fixed at rdf:Statement |
* String |
Entity | |
name: A human-readable name for an attribute or entity. |
0..1 LabelType |
Entity | |
description: a human-readable description of an entity |
0..1 NarrativeText |
Entity | |
has_attribute: connects any entity to an attribute |
* Attribute |
Entity | |
deprecated: A boolean flag indicating that an entity is no longer considered current or valid. |
0..1 Boolean |
Entity |
LinkML Source
name: reaction to catalyst association
from_schema: https://w3id.org/biolink/biolink-model
is_a: reaction to participant association
slot_usage:
object:
name: object
range: gene or gene product