Class: EntityToFeatureOrDiseaseQualifiersMixin
Description: Qualifiers for entity to disease or phenotype associations.
 classDiagram
    class EntityToFeatureOrDiseaseQualifiersMixin
      FrequencyQualifierMixin <|-- EntityToFeatureOrDiseaseQualifiersMixin
      EntityToFeatureOrDiseaseQualifiersMixin <|-- ChemicalOrDrugOrTreatmentToDiseaseOrPhenotypicFeatureAssociation
      EntityToFeatureOrDiseaseQualifiersMixin <|-- EntityToPhenotypicFeatureAssociationMixin
      EntityToFeatureOrDiseaseQualifiersMixin <|-- EntityToDiseaseAssociationMixin
      EntityToFeatureOrDiseaseQualifiersMixin : disease_context_qualifier
          EntityToFeatureOrDiseaseQualifiersMixin --|> Disease : disease_context_qualifier
      EntityToFeatureOrDiseaseQualifiersMixin : frequency_qualifier
      EntityToFeatureOrDiseaseQualifiersMixin : object
          EntityToFeatureOrDiseaseQualifiersMixin --|> NamedThing : object
      EntityToFeatureOrDiseaseQualifiersMixin : object_aspect_qualifier
      EntityToFeatureOrDiseaseQualifiersMixin : object_direction_qualifier
          EntityToFeatureOrDiseaseQualifiersMixin --|> DirectionQualifierEnum : object_direction_qualifier
      EntityToFeatureOrDiseaseQualifiersMixin : predicate
      EntityToFeatureOrDiseaseQualifiersMixin : qualified_predicate
      EntityToFeatureOrDiseaseQualifiersMixin : subject
          EntityToFeatureOrDiseaseQualifiersMixin --|> NamedThing : subject
      EntityToFeatureOrDiseaseQualifiersMixin : subject_aspect_qualifier
      EntityToFeatureOrDiseaseQualifiersMixin : subject_direction_qualifier
          EntityToFeatureOrDiseaseQualifiersMixin --|> DirectionQualifierEnum : subject_direction_qualifier
Inheritance
- FrequencyQualifierMixin
- EntityToFeatureOrDiseaseQualifiersMixin
 
 
Slots
| Name | Cardinality and Range | Inheritance | Examples | 
|---|---|---|---|
| subject_aspect_qualifier:  Composes with the core concept to describe new concepts of a different ontological type. e.g. a process in which the core concept participates, a function/activity/role held by the core concept, or a characteristic/quality that inheres in the core concept. The purpose of the aspect slot is to indicate what aspect is being affected in an 'affects' association. This qualifier specifies a change in the subject of an association (aka: statement).  | 
0..1  String  | 
direct | stability, abundance, expression, exposure | 
| subject_direction_qualifier:  Composes with the core concept (+ aspect if provided) to describe a change in its direction or degree. This qualifier qualifies the subject of an association (aka: statement).  | 
0..1  DirectionQualifierEnum  | 
direct | |
| object_aspect_qualifier:  Composes with the core concept to describe new concepts of a different ontological type. e.g. a process in which the core concept participates, a function/activity/role held by the core concept, or a characteristic/quality that inheres in the core concept. The purpose of the aspect slot is to indicate what aspect is being affected in an 'affects' association. This qualifier specifies a change in the object of an association (aka: statement).  | 
0..1  String  | 
direct | stability, abundance, expression, exposure | 
| object_direction_qualifier:  Composes with the core concept (+ aspect if provided) to describe a change in its direction or degree. This qualifier qualifies the object of an association (aka: statement).  | 
0..1  DirectionQualifierEnum  | 
direct | |
| qualified_predicate:  Predicate to be used in an association when subject and object qualifiers are present and the full reading of the statement requires a qualification to the predicate in use in order to refine or increase the specificity of the full statement reading. This qualifier holds a relationship to be used instead of that expressed by the primary predicate, in a ‘full statement’ reading of the association, where qualifier-based semantics are included. This is necessary only in cases where the primary predicate does not work in a full statement reading.  | 
0..1  String  | 
direct | |
| disease_context_qualifier:  A context qualifier representing a disease or condition in which a relationship expressed in an association took place.  | 
0..1  Disease  | 
direct | MONDO:0004979, MONDO:0005148 | 
| frequency_qualifier:  a qualifier used in a phenotypic association to state how frequent the phenotype is observed in the subject  | 
0..1  FrequencyValue  | 
FrequencyQualifierMixin | |
| subject:  connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.  | 
1  NamedThing  | 
FrequencyQualifierMixin | |
| predicate:  A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.  | 
1  PredicateType  | 
FrequencyQualifierMixin | |
| object:  connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.  | 
1  NamedThing  | 
FrequencyQualifierMixin | 
Mixin Usage
| mixed into | description | 
|---|---|
| ChemicalOrDrugOrTreatmentToDiseaseOrPhenotypicFeatureAssociation | This association defines a relationship between a chemical or treatment (or procedure) and a disease or phenotypic feature where the disease or phenotypic feature is a secondary undesirable effect. | 
LinkML Source
name: entity to feature or disease qualifiers mixin
description: Qualifiers for entity to disease or phenotype associations.
from_schema: https://w3id.org/biolink/biolink-model
is_a: frequency qualifier mixin
mixin: true
slots:
- subject aspect qualifier
- subject direction qualifier
- object aspect qualifier
- object direction qualifier
- qualified predicate
- disease context qualifier