Class: DrugToGeneInteractionExposure
Description: drug to gene interaction exposure is a drug exposure is where the interactions of the drug with specific genes are known to constitute an 'exposure' to the organism, leading to or influencing an outcome.
classDiagram
class DrugToGeneInteractionExposure
GeneGroupingMixin <|-- DrugToGeneInteractionExposure
DrugExposure <|-- DrugToGeneInteractionExposure
DrugToGeneInteractionExposure : category
DrugToGeneInteractionExposure : deprecated
DrugToGeneInteractionExposure : description
DrugToGeneInteractionExposure : equivalent_identifiers
DrugToGeneInteractionExposure : exposure_additional_condition
DrugToGeneInteractionExposure : exposure_duration
DrugToGeneInteractionExposure : exposure_end_age
DrugToGeneInteractionExposure : exposure_magnitude
DrugToGeneInteractionExposure : exposure_route
DrugToGeneInteractionExposure : exposure_start_age
DrugToGeneInteractionExposure : exposure_type
DrugToGeneInteractionExposure : exposure_vehicle
DrugToGeneInteractionExposure : full_name
DrugToGeneInteractionExposure : has_attribute
DrugToGeneInteractionExposure --|> Attribute : has_attribute
DrugToGeneInteractionExposure : has_gene_or_gene_product
DrugToGeneInteractionExposure --|> Gene : has_gene_or_gene_product
DrugToGeneInteractionExposure : has_quantitative_value
DrugToGeneInteractionExposure --|> QuantityValue : has_quantitative_value
DrugToGeneInteractionExposure : id
DrugToGeneInteractionExposure : information_content
DrugToGeneInteractionExposure : iri
DrugToGeneInteractionExposure : name
DrugToGeneInteractionExposure : provided_by
DrugToGeneInteractionExposure : synonym
DrugToGeneInteractionExposure : taxon
DrugToGeneInteractionExposure : timepoint
DrugToGeneInteractionExposure : type
DrugToGeneInteractionExposure : xref
Inheritance
- Entity
- NamedThing
- ExposureEvent [ OntologyClass]
- ChemicalExposure
- DrugExposure
- DrugToGeneInteractionExposure [ GeneGroupingMixin]
- DrugExposure
- ChemicalExposure
- ExposureEvent [ OntologyClass]
- NamedThing
Slots
| Name | Cardinality and Range | Inheritance | Examples |
|---|---|---|---|
| has_gene_or_gene_product: connects an entity with one or more gene or gene products |
* Gene |
GeneGroupingMixin | |
| has_quantitative_value: connects an attribute to a value |
* QuantityValue |
ChemicalExposure | |
| timepoint: a point in time |
0..1 TimeType |
ExposureEvent | |
| exposure_type: Type of exposure |
0..1 String |
ExposureEvent | |
| exposure_vehicle: Type of an exposure event. |
0..1 String |
ExposureEvent | |
| exposure_route: Route of exposure. |
0..1 String |
ExposureEvent | |
| exposure_start_age: Starting age of an exposure event. |
0..1 Integer |
ExposureEvent | |
| exposure_end_age: Ending stage of an exposure event. |
0..1 Integer |
ExposureEvent | |
| exposure_duration: Duration of an exposure event. |
0..1 Time |
ExposureEvent | |
| exposure_magnitude: Magnitude of an exposure event, e.g, parts per million of a toxic chemical. |
0..1 String |
ExposureEvent | |
| exposure_additional_condition: Additional conditions impacting an exposure event. |
0..1 String |
ExposureEvent | |
| id: Could generally be a CURIE from a suitable exposure ontology like ECTO. |
1 String |
Entity, OntologyClass | |
| provided_by: The value in this node property represents the knowledge provider that created or assembled the node and all of its attributes. Used internally to represent how a particular node made its way into a knowledge provider or graph. |
* String |
NamedThing | |
| xref: A database cross reference or alternative identifier for a NamedThing or edge between two NamedThings. This property should point to a database record or webpage that supports the existence of the edge, or gives more detail about the edge. This property can be used on a node or edge to provide multiple URIs or CURIE cross references. |
* Uriorcurie |
NamedThing | |
| full_name: a long-form human readable name for a thing |
0..1 LabelType |
NamedThing | |
| synonym: Alternate human-readable names for a thing |
* LabelType |
NamedThing | |
| equivalent_identifiers: A set of identifiers that are considered equivalent to the primary identifier of the entity. This attribute is used to represent a collection of identifiers that are considered equivalent to the primary identifier of an entity. These equivalent identifiers may come from different databases, ontologies, or naming conventions, but they all refer to the same underlying concept or entity. This attribute is particularly useful in data integration and interoperability scenarios, where it is important to recognize and link different representations of the same entity across various sources. |
* Uriorcurie |
NamedThing | |
| information_content: Information content (IC) value for a term, primarily from Automats. |
0..1 Float |
NamedThing | |
| taxon: A property that indicates the taxonomic classification of an entity. Values for this slot should be from the NCBITaxon ontology. |
0..1 Uriorcurie |
NamedThing | |
| iri: An IRI for an entity. This is determined by the id using expansion rules. |
0..1 IriType |
Entity | |
| category: Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class. In a neo4j database this MAY correspond to the neo4j label tag. In an RDF database it should be a biolink model class URI. This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values biolink:Protein, biolink:GeneProduct, biolink:MolecularEntity. In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature f may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing} |
1..* Uriorcurie |
Entity | |
| type: None |
* String |
Entity | |
| name: A human-readable name for an attribute or entity. |
0..1 LabelType |
Entity | |
| description: a human-readable description of an entity |
0..1 NarrativeText |
Entity | |
| has_attribute: connects any entity to an attribute |
* Attribute |
Entity | |
| deprecated: A boolean flag indicating that an entity is no longer considered current or valid. |
0..1 Boolean |
Entity |
LinkML Source
name: drug to gene interaction exposure
description: drug to gene interaction exposure is a drug exposure is where the interactions
of the drug with specific genes are known to constitute an 'exposure' to the organism,
leading to or influencing an outcome.
from_schema: https://w3id.org/biolink/vocab/
is_a: drug exposure
mixins:
- gene grouping mixin