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Class: ChemicalToEntityAssociationMixin

Description: An interaction between a chemical entity and another entity
classDiagram class ChemicalToEntityAssociationMixin ChemicalEntityToEntityAssociationMixin <|-- ChemicalToEntityAssociationMixin ChemicalToEntityAssociationMixin <|-- ChemicalToChemicalAssociation ChemicalToEntityAssociationMixin <|-- ChemicalToDiseaseOrPhenotypicFeatureAssociation ChemicalToEntityAssociationMixin <|-- ChemicalOrDrugOrTreatmentToDiseaseOrPhenotypicFeatureAssociation ChemicalToEntityAssociationMixin <|-- ChemicalOrDrugOrTreatmentSideEffectDiseaseOrPhenotypicFeatureAssociation ChemicalToEntityAssociationMixin <|-- ChemicalToPathwayAssociation ChemicalToEntityAssociationMixin <|-- ChemicalGeneInteractionAssociation ChemicalToEntityAssociationMixin : object ChemicalToEntityAssociationMixin --|> NamedThing : object ChemicalToEntityAssociationMixin : predicate ChemicalToEntityAssociationMixin : subject ChemicalToEntityAssociationMixin --|> ChemicalEntityOrGeneOrGeneProduct : subject

Inheritance

Slots

Name Cardinality and Range Inheritance Examples
subject:
the chemical entity or entity that is an interactor
1
ChemicalEntityOrGeneOrGeneProduct
direct
predicate:
A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.
1
PredicateType
direct
object:
connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.
1
NamedThing
direct

Mixin Usage

mixed into description
ChemicalToChemicalAssociation A relationship between two chemical entities. This can encompass actual interactions as well as temporal causal edges, e.g. one chemical converted to another.
ChemicalToDiseaseOrPhenotypicFeatureAssociation An interaction between a chemical entity and a phenotype or disease, where the presence of the chemical gives rise to or exacerbates the phenotype.
ChemicalOrDrugOrTreatmentToDiseaseOrPhenotypicFeatureAssociation This association defines a relationship between a chemical or treatment (or procedure) and a disease or phenotypic feature where the disease or phenotypic feature is a secondary undesirable effect.
ChemicalOrDrugOrTreatmentSideEffectDiseaseOrPhenotypicFeatureAssociation This association defines a relationship between a chemical or treatment (or procedure) and a disease or phenotypic feature where the disesae or phenotypic feature is a secondary, typically (but not always) undesirable effect.
ChemicalToPathwayAssociation An interaction between a chemical entity and a biological process or pathway.
ChemicalGeneInteractionAssociation describes a physical interaction between a chemical entity and a gene or gene product. Any biological or chemical effect resulting from such an interaction are out of scope, and covered by the ChemicalAffectsGeneAssociation type (e.g. impact of a chemical on the abundance, activity, structure, etc, of either participant in the interaction)

LinkML Source

name: chemical to entity association mixin
description: An interaction between a chemical entity and another entity
from_schema: https://w3id.org/biolink/biolink-model
is_a: chemical entity to entity association mixin
mixin: true
slots:
- subject
- predicate
- object
slot_usage:
  subject:
    name: subject
    description: the chemical entity or entity that is an interactor
    range: chemical entity or gene or gene product
defining_slots:
- subject